Posted: 29-Oct-23

Location: San Francisco, California

Type: Full-time

Salary: Open

Categories:

Internal Number: 74961BR

The laboratory of Matt State at the University of California, San Francisco is seeking a creative, independent, and team-oriented bioinformatics programmer to join our group. The State lab focuses on defining the etiology of childhood neuropsychiatric disorders, with particular interest in autism spectrum disorder, schizophrenia, OCD, and Tourette Disorder. You will work on developing infrastructure updating data analysis pipelines for high throughput experiments and creating novel computational methods that integrate in-house and publicly available datasets related to neurodevelopmental and psychiatric disorders. You will work with Ph.D. and postdoctoral-level bioinformaticians and wet lab scientists within our group and collaborating groups to further this research and support the computing needs of the laboratory. While experience in biology and genetics would be a great asset, we are especially keen to hire an individual who is highly motivated with a positive attitude and team mentality, excellent organizational skills, an affinity for independent problem-solving, and the ability to learn and implement new methodologies efficiently.
Utilize and develop computational tools and statistical methodologies to analyze and interpret data generated through high-throughput experiments; in-house data types include single-cell/nucleus RNA sequencing data, protein-protein interaction data (generated via AP-MS), and whole exome sequencing data. Collaborate with wet lab researchers on the experimental and statistical design of projects and in the biological interpretation and integration of the resulting datasets. Use and adapt in-house analysis pipelines (currently mostly in the R programming language) to perform data analysis steps including data quality checks, normalization, statistical tests, correction for multiple testing, and further downstream analyses that integrate additional external datasets. Implement end-user needs in database searching and integration and provide web-based bioinformatics and access to public and proprietary databases. Help maintain the computational infrastructure and track the flow of samples and information for large-scale studies.
To see the salary range for this position (we recommend that you make a note of the job code and use that to look up): TCS Non-Academic Titles Search (ucop.edu) Please note: The compensation ranges listed online for roles not covered by a bargaining unit agreement are very wide, however a job offer will typically fall in the range of 80% - 120% of the established mid-point. An offer will take into consideration the experience of the final candidate AND the current salary level of individuals working at UCSF in a similar role. For roles covered by a bargaining unit agreement, there will be specific rules about where a new hire would be placed on the range. To learn more about the benefits of working at UCSF, including total compensation, please visit: https://ucnet.universityofcalifornia.edu/compensation-and-benefits/index.html